Is radioimmunotherapy a 'magic bullet'?
نویسنده
چکیده
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fig. 1. Radioimmunotherapy (RIT) using monoclonal antibodies labeled with a radioisotope emitting gammaor betarays. http://dx.doi.org/10.5045/kjh.2012.47.2.85 The Korean Journal of Hematology Volume 47ᆞNumber 2ᆞJune 2012
منابع مشابه
Monoclonal antibody-based therapies for microbial diseases.
The monoclonal antibody (mAb) revolution that currently provides many new options for the treatment of neoplastic and inflammatory diseases has largely bypassed the field of infectious diseases. Only one mAb is licensed for use against an infectious disease, although there are many in various stages of development. This situation is peculiar given that serum therapy was one of the first effecti...
متن کاملEhrlich's Magic Bullet - and the Curse of Injections
Paul Ehrlich, the inventor of the Magic Bullet died, regretting the slaughter of the First World War. As biology students in the early 1940’s we all knew one important number, 606, the name of the first man-made drug, Salvarsan or the Magic Bullet. A German doctor, Paul Ehrlich, had noticed that different dyes would stain tissues and even bacteria and parasites. He noticed that methylene blue s...
متن کاملFrom Amazon rain forest flora to the state-of-the-art technology devices, the incessant search for 'magic bullets' against Streptococcus mutans
bacteria (and not by host cells), it could be the ‘magic bullet’ of his dreams7. After testing over nine hundred dyes and chemical compounds, the 606 compound (latter named Salvarsan) was found to be effective against the etiological agent of syphilis; but unfortunately such compound toxicity against the host was evidenced. While the ‘606’ comprised a huge advance in the war on microbes, it bec...
متن کاملSpecific drugs for a complex disease: can there be a magic bullet against rheumatoid arthritis?
The complexity of RA challenges our search for a better understanding of the interconnected networks. Early treatment will certainly avoid some of the problems presented by the complexity of the disease, and combined treatments seem advantageous for advanced disease. The complexity of overt RA will probably not allow a single agent to exert superior efficacy. Unless a treatable infectious cause...
متن کامل